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01-11-2017· (D) Platelet count was assessed by flow cytometry by mixing samples with counting beads. Mk pre-treatment with 10 μm AKT inhibitor (AKT inh) significantly reduced the number of collected platelets (scale bar = 2 cm). (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
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PLATELET-DERIVED GROWTH FACTOR-STIMULATED KINASE* (Received for publication, February 23, 1983) Carl-Henrik HeldinS, Bo Ek, and Lars Ronnstrand From the Department of Medical and Physiological Chemistry, Box 575, Biomedicum, S-751 23 Uppsala, Sweden The receptor for platelet-derived growth factor
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15-08-2008· There is no doubt that regulation of erythropoiesis is essential for maintaining oxygen homeostasis in vertebrates. Erythroid progenitors have the potential to proliferate rapidly in response to anemic and hypoxic stimuli, a process referred to as stress erythropoiesis. 9 Erythropoietin (Epo) and its receptor (EpoR) play central roles in this process. 9 Epo is a glycoprotein hormone produced ...
290 Platelet Disorders In the second paragraph, replace "which ranges from petechiae (1–2 mm, typically not seen in qualitative disorders), purpura (> 1 mm), ecchymoses (> 3 mm), to easy bruising" with "which ranges from petechiae (< 0.3 cm, typically not seen in qualitative disorders), purpura (0.3 cm–
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15-02-2005· Platelet agonists were collagen (Horm, type I from equine tendon; Nycomed, Munich, Germany); thrombin (Sigma, Poole, United Kingdom) and convulxin (convulxin was purified from snake venom and was a generous gift from Drs M. Leduc and C. Bon [Institut Pasteur, Paris, France]). Two venom preparations, with different potencies, were used.
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25-11-2010· Platelet activation is shown as the standardized residuals of logit transformed flow-cytometric measurement of the percentage of platelets positive for specific markers of activation, as previously described. 1 Graphs display the correlation with the highest significance, and boxes show Pearson correlation coefficients (r) and probability values (in parentheses) for all 4 functional …
25-07-2007· Platelet aggregation studies were conducted using an Aggregometer 490-2A (Chrono-log Co., Havertown, PA, USA). 500 μL of citrate–PRP, CTI–citrate–PRP or CTI–PRP and its matching PPP (background control) were added to four cuvettes in the aggregometer and allowed to stabilize at 37 °C for 5 min. Platelet aggregation was initiated by the addition of one agonist to each cuvette in the ...